Micheline Piquette-MillerProfile page
Professor
Leslie Dan Faculty of Pharmacy
BIO
Dr. Piquette-Miller is the Associate Dean, Research and Professor at the Leslie Dan Faculty of Pharmacy, and has cross-appointment with the Department of Pharmacology & Toxicology, in the Temerty Faculty of Medicine. She completed her PhD in Pharmacokinetics at the University of Alberta and Postdoctoral Fellowship at the University of California, San Francisco.
Since joining the Faculty in 1996, Professor Piquette-Miller has been leading a dynamic research lab that specializes in understanding how pathophysiological conditions affect the efficacy and safety of drugs, particularly in the context of drug-disease interactions involving drug transporters. As fetal exposure to some drugs and other potentially harmful substances circulating in the mother’s blood depends on the function and regulation of transport proteins at the placental barrier, her research focuses on understanding the regulation of these proteins in the human placenta. Using in vitro cell and tissue models and experimental animal models, her lab studies ABC and SLC transporters that are involved in the passage of drugs, toxins, hormones, and nutrients that could possibly affect maternal and fetal health.
Dr. Piquette-Miller has published over 130 research articles and recently contributed expertise as a member of the COVID-19 Clinical Pharmacology Ad-hoc Task Force for the Public Health Agency of Canada. She is also the recipient of numerous prestigious national and international research awards including The Leon Goldberg Young Investigator Award, American Society for Clinical Pharmacology and Therapeutics (ASCPT), Canadian Society of Pharmaceutical Sciences Fellow Award, RX&D/Canadian Institutes of Health Research (CIHR) Research Career Award and Pfizer Research Career Award, Association of Pharmaceutical Sciences (AFPC). In addition, she did a sabbatical with the American Food and Drug Association (FDA) to help develop industry guidelines for conducting drug-drug interaction studies.
Media availability: TV, Radio, Print/Online
Keywords: pharmacokinetics, clinical and molecular pharmacology, drug transporters, drug disposition, maternal-fetal health, placenta, inflammation, autoimmune disease, preeclampsia, women’s health, ovarian cancer, breast cancer.
Since joining the Faculty in 1996, Professor Piquette-Miller has been leading a dynamic research lab that specializes in understanding how pathophysiological conditions affect the efficacy and safety of drugs, particularly in the context of drug-disease interactions involving drug transporters. As fetal exposure to some drugs and other potentially harmful substances circulating in the mother’s blood depends on the function and regulation of transport proteins at the placental barrier, her research focuses on understanding the regulation of these proteins in the human placenta. Using in vitro cell and tissue models and experimental animal models, her lab studies ABC and SLC transporters that are involved in the passage of drugs, toxins, hormones, and nutrients that could possibly affect maternal and fetal health.
Dr. Piquette-Miller has published over 130 research articles and recently contributed expertise as a member of the COVID-19 Clinical Pharmacology Ad-hoc Task Force for the Public Health Agency of Canada. She is also the recipient of numerous prestigious national and international research awards including The Leon Goldberg Young Investigator Award, American Society for Clinical Pharmacology and Therapeutics (ASCPT), Canadian Society of Pharmaceutical Sciences Fellow Award, RX&D/Canadian Institutes of Health Research (CIHR) Research Career Award and Pfizer Research Career Award, Association of Pharmaceutical Sciences (AFPC). In addition, she did a sabbatical with the American Food and Drug Association (FDA) to help develop industry guidelines for conducting drug-drug interaction studies.
Media availability: TV, Radio, Print/Online
Keywords: pharmacokinetics, clinical and molecular pharmacology, drug transporters, drug disposition, maternal-fetal health, placenta, inflammation, autoimmune disease, preeclampsia, women’s health, ovarian cancer, breast cancer.
ACADEMIC POSITIONS
- Acting DeanUniversity of Toronto, Leslie Dan Faculty of Pharmacy, Toronto, CanadaSep 2023 - Dec 2023
- Associate DeanUniversity of Toronto, Leslie Dan Faculty of Pharmacy, Toronto, CanadaNov 2021 - present
- ProfessorUniversity of Toronto, Leslie Dan Faculty of Pharmacy, Toronto, CanadaJul 2007 - present
- Cross-appointment, Associate ProfessorUniversity of Toronto, Department of Pharmacology and Toxicology, Faculty of Medicine, Toronto, CanadaJul 2001 - present
- Interim DirectorUniversity of Toronto, Graduate Department of Pharmaceutical Sciences, Toronto, Canada1 Jul 2020 - Jul 2021
- Graduate & Research Field CoordinatorUniversity of Toronto, Biomolecular Sciences, Dept. Pharmaceutical Sciences, Toronto, CanadaJul 2017 - Oct 2021
- DirectorUniversity of Toronto, Leslie Dan Faculty of Pharmacy, Division of Biomolecular Research, Toronto, CanadaSep 2005 - Jun 2008
- Associate ProfessorUniversity of Toronto, Leslie Dan Faculty of Pharmacy, Toronto, CanadaJul 2001 - Jun 2007
- Assistant ProfessorUniversity of Toronto, Leslie Dan Faculty of Pharmacy, Toronto, CanadaJul 1996 - Jun 2001
DEGREES
- Ph.D. Pharmaceutical Sciences (Pharmacokinetics)University of Alberta, Edmonton, Canada
- B.Sc., PharmacyUniversity of Alberta, Edmonton, Canada
POSTGRADUATE TRAINING
- Postdoctoral FellowUniversity of California, San Francisco, Department of Biopharmaceutics & Molecular Pharmacology, San Francisco, United StatesSupervised by Dr. K. Giacomini
LANGUAGES
- English
AVAILABILITY
- Media enquiries
- Masters Research or PhD student supervision
INSTITUTIONAL STRATEGIC INITIATIVES
- PRiME (Precision Medicine Initiative)
- Data Sciences Institute (DSI)