Micheline Piquette-Miller

Dr. Piquette-Miller is the Associate Dean, Research and Professor at the Leslie Dan Faculty of Pharmacy, and has cross-appointment with the Department of Pharmacology & Toxicology, in the Temerty Faculty of Medicine. She completed her PhD in Pharmacokinetics at the University of Alberta and Postdoctoral Fellowship at the University of California, San Francisco.

Since joining the Faculty in 1996, Professor Piquette-Miller has been leading a dynamic research lab that specializes in understanding how pathophysiological conditions affect the efficacy and safety of drugs, particularly in the context of drug-disease interactions involving drug transporters. As fetal exposure to some drugs and other potentially harmful substances circulating in the mother’s blood depends on the function and regulation of transport proteins at the placental barrier, her research focuses on understanding the regulation of these proteins in the human placenta. Using in vitro cell and tissue models and experimental animal models, her lab studies ABC and SLC transporters that are involved in the passage of drugs, toxins, hormones, and nutrients that could possibly affect maternal and fetal health.

Dr. Piquette-Miller has published over 130 research articles and recently contributed expertise as a member of the COVID-19 Clinical Pharmacology Ad-hoc Task Force for the Public Health Agency of Canada. She is also the recipient of numerous prestigious national and international research awards including The Leon Goldberg Young Investigator Award, American Society for Clinical Pharmacology and Therapeutics (ASCPT), Canadian Society of Pharmaceutical Sciences Fellow Award, RX&D/Canadian Institutes of Health Research (CIHR) Research Career Award and Pfizer Research Career Award, Association of Pharmaceutical Sciences (AFPC). In addition, she did a sabbatical with the American Food and Drug Association (FDA) to help develop industry guidelines for conducting drug-drug interaction studies.

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Keywords: pharmacokinetics, clinical and molecular pharmacology, drug transporters, drug disposition, maternal-fetal health, placenta, inflammation, autoimmune disease, preeclampsia, women’s health, ovarian cancer, breast cancer.